Next-generation PRP. Deeper results. Longer lasting.
PRF (Platelet Rich Fibrin) is an evolution of PRP — prepared differently to create a fibrin scaffold that releases growth factors over days, not hours. Deeper collagen remodeling, higher concentration, more durable results.
PRF treats the same concerns as PRP — but deeper, longer, and with more growth factors.
The fibrin scaffold in PRF acts as a slow-release delivery system. Growth factors don't dissipate within hours — they continue working in the tissue for 7–14 days, stimulating collagen and elastin production at a depth and duration that standard PRP can't match.
For patients who've had PRP and want to go further — or who want the strongest regenerative result from the start. PRF's sustained growth factor release triggers a more prolonged and deeper fibroblast response than standard PRP, producing measurable increases in dermal collagen density over 3–6 months.
One of PRF's most impactful applications. The fibrin matrix can be injected under the eyes as a natural alternative to hyaluronic acid filler — integrating with the tissue rather than sitting in it. For patients who've had filler migration or want an autologous approach, PRF under-eye treatment produces a gradual, natural-looking improvement without the risk of filler-related complications.
PRF injected along the jawline and at the pre-jowl area provides both volume (the fibrin matrix has physical substance) and collagen stimulation — improving definition and firmness simultaneously. A natural-material alternative to HA filler for patients who prefer entirely autologous treatment.
The same indications as PRP — firmness, texture, dullness, fine lines — addressed with the enhanced growth factor concentration and sustained release of PRF. Patients who've already completed a PRP series often transition to PRF for their ongoing maintenance to sustain and deepen the collagen baseline they've established.
PRF applied alongside or after PDO thread treatment amplifies the collagen-stimulating effect — the growth factors work synergistically with the thread's inflammatory response to produce more significant and longer-lasting collagen formation than either treatment alone.
For patients who are poor candidates for HA filler due to vascular anatomy concerns, filler migration history, or personal preference for entirely natural material, PRF offers a regenerative alternative that produces improvement without introducing any foreign substance.
PRF therapy for hair loss is an increasingly sought-after alternative to expensive hair transplantation — affecting both men and women as early as their twenties. PRF extracted from your own blood contains a potent blend of white blood cells, fibrin, stem cells, and growth factors. Injected into the scalp, it improves scalp health, stimulates hair follicle activity, and promotes regrowth of thinning hair. Because PRF is additive-free and derived from your own blood, it carries no rejection risk. The cost is several times lower than hair transplant procedures.
If you want the deepest regenerative treatment available using your own biology, PRF is the most advanced option.
PRF represents the current state of the art in autologous growth factor therapy. It takes the mechanism of PRP and makes it more concentrated, more targeted, and more durable — using nothing but your own blood.
The same mechanism as PRP — but more of everything.
PRF and PRP are both prepared from your own blood by centrifugation — but the preparation protocol is fundamentally different. PRP uses anticoagulants and a high centrifuge speed that separates plasma rapidly, producing a liquid that releases growth factors within minutes to hours of injection. PRF is centrifuged more slowly, without anticoagulants — allowing the natural coagulation process to form a fibrin scaffold that physically traps platelets, white blood cells, and growth factors in a three-dimensional matrix. Because PRF is prepared from your own blood with no additives or external agents, it is one of the most natural cosmetic treatments available — zero risk of allergic reaction or rejection.
This fibrin matrix is the key to PRF's enhanced effect. Rather than releasing growth factors in a single burst, the matrix releases them continuously over 7–14 days as it gradually breaks down. This sustained release maintains fibroblast stimulation over a much longer window than PRP, producing deeper and more durable collagen synthesis. The slower centrifuge speed also preserves a higher concentration of leukocytes (white blood cells) and platelets — meaning more growth factors per unit volume than standard PRP.
When used as an injectable filler alternative (particularly under the eyes or along the jawline), PRF has a physical substance from the fibrin matrix that provides immediate soft-tissue support — while simultaneously stimulating new collagen and elastin in the surrounding tissue. This dual mechanism — immediate volume plus long-term regeneration — is unique to PRF among autologous treatments.
We recommend PRF over standard PRP when: (1) the patient wants the most significant regenerative result achievable; (2) the target area is the tear trough or jawline where injectable volume plus collagen stimulation is the goal; (3) the patient has completed a PRP series and wants to go deeper; (4) filler is contraindicated or the patient prefers autologous material. Your physician will recommend the right modality based on your specific goals and anatomy.
PRP vs. PRF — understanding the difference.
Both use your own blood. The difference is in how they're prepared — and what that means for depth, duration, and concentration of the therapeutic effect.
| Feature | PRF ★ | PRP |
|---|---|---|
| Preparation | No anticoagulants, slow centrifuge | With anticoagulants, faster centrifuge |
| Result form | Fibrin matrix (semi-solid) | Liquid plasma |
| Growth factor release | 7–14+ days sustained | Minutes to hours |
| GF concentration | Higher (leukocytes preserved) | Standard concentration |
| Can replace HA filler? | ✓ Under eyes, jawline | ✗ No physical volume |
| Collagen effect depth | Deeper and more durable | Moderate |
| Results duration | 12–24 months | 12–18 months |
| Autologous (own blood) | ✓ Yes | ✓ Yes |
PRF represents the current state of the art in regenerative aesthetics.
The scientific basis for PRF is well-established in wound healing and surgical literature — its application in facial aesthetics is now supported by a growing body of clinical evidence demonstrating superior collagen outcomes compared to standard PRP.
From blood draw to your deepest result.
We assess your goals, review your anatomy (particularly for tear trough and jawline applications), and design your PRF protocol — number of sessions, application sites, and any combination with other treatments.
Small blood draw in our clinical setting. Centrifuged at a lower speed without anticoagulants — producing the fibrin matrix that makes PRF distinct from PRP. Preparation takes 10–15 minutes The centrifuge process takes approximately 10 minutes — after which the PRF is used immediately to maximize the effectiveness of the cosmetic enhancement.
Injected into target areas (tear troughs, jawline, general skin quality treatment via microneedling). Very fine needles. Topical or local anesthetic used for sensitive areas. 45–60 minutes total.
2–3 sessions spaced 4–6 weeks apart for optimal collagen response. Full effect visible at 4–6 months. Annual maintenance sustains results. Often combined with other treatments in a comprehensive rejuvenation protocol.
Medicine that
gets you.
PRF preparation quality and injection technique are everything. A suboptimal centrifuge protocol produces a suboptimal fibrin matrix — which is why clinical training and precision preparation matter as much as the treatment itself.
Validated Centrifuge Protocol
PRF quality depends on the exact centrifuge speed and time. We follow protocols validated in the clinical literature for optimal fibrin matrix formation and growth factor preservation — not a generic spinning protocol.
Anatomy-First Tear Trough Approach
Under-eye PRF requires a detailed understanding of periorbital anatomy — the same vascular considerations that apply to tear trough filler. Our physicians are trained in both, which is why this application is safe and produces natural results in our hands.
100% Autologous — No Foreign Material
PRF contains nothing but your own blood's components. Zero risk of allergic reaction, immune rejection, or material-related complications. For patients with concerns about introducing foreign substances, PRF offers a complete alternative.
PRF as Part of a Strategy
We don't offer PRF as an isolated treatment — we design it as part of a broader protocol. PRF works best in sequence with other modalities (HydraFacial, threads, PRP) and we'll plan the right combination and timing for your specific goals.
Real patients.
Real results.
Everything you
want to know.
The deepest regenerative result
from your own biology.
A free consultation and honest assessment of what PRF can achieve for your specific goals — including whether PRP, PRF, or a combination is the right starting point.