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iControl Weight Loss Program
"I know what to eat. The problem is my brain won't let me stop craving the wrong things. I need something that changes that."

Your cravings are a brain problem. We treat the brain.

The iControl Weight Loss Program uses Naltrexone and Bupropion to modify the way your brain's reward and hunger systems respond to food — making it easier to resist cravings, reduce appetite, and sustain the results you achieve. No surgery. Pharmaceutical treatment for the biology of obesity.

Food cravings that override willpower — chips, sugar, processed foods you can't resist
Obesity or overweight driven by reward-system eating patterns
History of yo-yo dieting — losing weight but unable to sustain it
Depression or mood issues alongside weight gain — Bupropion addresses both
iControl weight loss program at IUVENTUS Medical Center Las Vegas
Mechanism
Brain reward system
modifies how pleasure center responds to food
Naltrexone + Bupropion
FDA-approved components · Las Vegas
What it treats

Most diets fail because they fight the brain. iControl changes the brain.

The reason strict diets rarely work long-term is neurological — the brain's reward system works against caloric restriction. iControl targets this directly, modifying how the pleasure center responds to food consumption.

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Food Cravings & Reward-Driven Eating

The brain's reward system — the same pathway activated by addictive substances — responds to certain foods by triggering compulsive cravings. Naltrexone, an opioid antagonist, blocks these receptors without activating them — inhibiting the reward signal that drives food cravings. The result is that the compulsion to eat chips or donuts when your brain signals you to do so becomes significantly less powerful.

😰
Stress-Related & Emotional Eating

Obesity from acute stress and emotional eating responds particularly well to the Naltrexone-Bupropion combination because both medications address the neurological drivers of stress-induced food-seeking behavior. Whether your weight gain is driven by genetics, stress, or both — the iControl program is designed to modify the hunger system regardless of its original cause.

😔
Depression & Low Mood Alongside Weight Gain

Bupropion is an antidepressant that has been used for mild-to-severe depressive disorders for many years. In obesity treatment, it affects the food reward center and reduces appetite — but for patients where low mood and weight gain are intertwined, Bupropion addresses both simultaneously. Many patients find that the mood improvement from Bupropion makes the weight loss program significantly easier to adhere to.

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Failed Diets & Unsustained Weight Loss

The most common reason diets fail is not lack of knowledge — it is the brain's reward system working against sustained dietary restriction. iControl is specifically designed for patients who know how to eat well but cannot sustain it because their brain's pleasure center overrides their intentions. The program changes the neurological dynamic rather than asking for more willpower.

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General Obesity Treatment

For patients with general obesity — regardless of the cause — iControl provides a pharmaceutical framework that makes behavior change achievable. One out of three adults in the US has excess weight. Many maintain unhealthy eating habits that put them at risk of diabetes, heart attack, and stroke. The iControl program addresses the neurological root of these habits.

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Alcohol Craving Inhibition Crossover

Low-dose Naltrexone is prescribed for alcohol addiction — and its inhibition effects on the opioid reward pathway carry over to food cravings through the same mechanism. For patients with a history of addictive behavior patterns — including food addiction — Naltrexone's receptor-blocking effect addresses the craving mechanism at its neurological source.

Obesity doesn't define you — but the brain's reward system may be working against you. iControl changes that equation.

Before starting the iControl program, consultation with one of our providers is required. Not all patients can be prescribed Naltrexone and Bupropion — contraindications include cardiovascular diseases, diabetes, and seizure disorders. We confirm your candidacy before recommending the program.

iControl Naltrexone Bupropion mechanism at IUVENTUS Medical Center
How it works

Two medications. One system. Your food reward center.

The iControl Weight Loss Program combines two pharmaceutical agents that work synergistically on the brain's hunger and reward systems. Naltrexone is an opioid antagonist — it acts on opioid receptors without activating them, blocking the reward signal that those receptors produce in response to food. This is the same mechanism used to treat alcohol and opioid addiction — Naltrexone inhibits the neurological reward that drives compulsive consumption, whether the trigger is alcohol or calorie-dense food.

Bupropion is an antidepressant and smoking cessation medication that acts on dopamine and norepinephrine pathways. In obesity treatment, it affects the food reward center and reduces appetite through its action on the hypothalamus — the brain region that controls hunger and satiety signaling. In combination, Naltrexone and Bupropion create a synergistic effect that is significantly more powerful than either medication alone — they are the active components of FDA-approved combination weight loss medication.

The key difference from diet-based approaches is mechanism: iControl doesn't ask you to use willpower against your brain's reward system — it changes how your brain's reward system responds to food. For patients whose weight is driven by the neurological dynamics of craving and reward rather than simply caloric math, this is a fundamentally different — and more effective — intervention.

Naltrexone
opioid antagonist — blocks food reward signals without activating receptors
Bupropion
dopamine/norepinephrine modulator — reduces appetite via hypothalamic pathway
Synergistic
combination produces effects greater than either medication alone
⚠️
Candidacy assessment required — not suitable for everyone

Contraindications include: cardiovascular diseases, uncontrolled hypertension, type 2 diabetes (depending on medications), seizure disorders, eating disorders (bulimia/anorexia), current use of opioid medications, and pregnancy. A physician consultation is mandatory before starting the iControl program. We assess your complete medical history and confirm candidacy before prescribing.

The research is clear

The most promising pharmaceutical treatment for neurological obesity.

For patients whose weight is driven by the brain's reward system rather than simple caloric imbalance, pharmaceutical modification of that system is more effective than behavioral intervention alone. The Naltrexone-Bupropion combination targets the neurological root of food cravings.

1 in 3
US adults have excess weight — millions driven by the brain's reward system, not just caloric habits
CDC, National Center for Health Statistics
Naltrexone
Blocks opioid food reward signals — same mechanism proven in alcohol addiction treatment
Pharmacology literature
Bupropion
FDA-approved antidepressant that affects food reward center and reduces appetite via hypothalamic pathway
FDA labeling
How It Works

From fighting cravings to controlling them.

01
🗓️
Medical Consultation

A mandatory consultation with one of our providers before starting the program. We review your health history, confirm candidacy, and check for contraindications — cardiovascular disease, seizure disorders, current medications, and other factors that affect whether Naltrexone-Bupropion is appropriate for you.

02
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Pharmaceutical Protocol

Naltrexone and Bupropion prescribed at doses appropriate for your weight management goals. Dose is typically titrated upward to minimize side effects during adjustment. Most patients are on the full protocol within 4 weeks.

03
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Behavioral Support

The medications make resisting cravings significantly easier — we build on this with guidance on food choices and eating patterns. The goal is to use the window of reduced craving to establish the habits that make results lasting after the pharmaceutical support is tapered.

04
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Monitoring & Adjustment

Regular check-ins throughout the program. Weight, side effects, and response assessed. The program is adjusted based on your individual response to the medication and the behavioral changes you're making.

Why Choose Us

Medicine that
gets you.

iControl modifies the neurological system that makes dieting so hard. Our physicians assess candidacy carefully and supervise the program throughout — because getting the pharmacology right is everything.

01

Treats the Cause, Not the Symptom

Most weight loss programs treat appetite with restriction. iControl treats the neurological reward system that drives appetite — the root cause for patients whose overeating is driven by craving rather than hunger.

02

Mandatory Candidacy Assessment

We don't prescribe Naltrexone-Bupropion without a thorough consultation. The contraindications are real and important. We confirm you're an appropriate candidate before starting — and if you're not, we recommend a better-suited program.

03

Body Transformation Without Surgery

Visit Iuventus and start your body transformation without surgeries. The iControl program provides pharmaceutical-level intervention for obesity with the access and convenience of an outpatient clinic.

04

Addresses Co-Occurring Conditions

For patients with depression alongside obesity — a common combination — Bupropion's antidepressant effect works simultaneously with its weight-loss mechanism. A single pharmaceutical intervention that addresses two intertwined conditions.

Patient Stories

Cravings controlled.
Weight lost..

★★★★★

"I knew exactly how to eat well. My problem was the cravings at night — they were overwhelming and I'd been losing the battle for years. iControl was the first thing that actually turned the volume down on those cravings. After six weeks I stopped reaching for the things that were killing my progress."

KM
Karen M.
iControl Program · 46 yrs · Las Vegas
★★★★★

"I have depression and my weight had climbed during a difficult period. My physician recommended iControl specifically because Bupropion addresses both the mood and the appetite. Three months in and I've lost 22 pounds and my mood is stabilized. Treating both together was the right call."

BL
Brian L.
iControl — Depression + Weight · 52 yrs
★★★★★

"Five attempts at dieting in three years. Each time I'd do well for weeks and then the cravings would win. My physician explained the reward-system mechanism and it finally made sense why willpower alone wasn't enough. iControl changed the neurological equation. I'm down 30 pounds and sustaining it."

TR
Teresa R.
iControl Weight Loss Program · 43 yrs
Common Questions

Everything you
want to know.

Naltrexone is an opioid receptor antagonist — it blocks opioid receptors without activating them, inhibiting the reward signal those receptors produce. Originally used to treat opioid and alcohol addiction, it carries the same craving-inhibition mechanism to food reward signaling. Bupropion is an antidepressant and smoking cessation medication that modulates dopamine and norepinephrine — in obesity treatment, it acts on the hypothalamus to reduce appetite and affect the food reward center. Together they are the active components of the FDA-approved combination weight loss medication Contrave®.
Contraindications include: cardiovascular disease (certain types), uncontrolled hypertension, type 2 diabetes (depending on medications), seizure disorders, current use of opioid medications (Naltrexone blocks their effect), eating disorders (bulimia or anorexia), pregnancy, and certain psychiatric medications. This is why a mandatory physician consultation precedes every iControl program — we cannot prescribe without reviewing your complete medical history.
Duration varies by patient and response. Most patients use the program for 3–6 months to achieve significant weight loss and establish the behavioral habits that sustain it. The medication is typically tapered — not stopped abruptly — as you approach your goal. Some patients use a maintenance protocol at lower doses. Your physician designs the exit strategy from the beginning of the program.
Common side effects during dose titration include nausea, headache, dizziness, insomnia, and dry mouth. These typically improve significantly as the body adjusts over 2–4 weeks. The dose titration protocol (starting low and increasing gradually) minimizes these effects. More serious side effects include elevated blood pressure and, rarely, seizure risk — which is why the contraindication assessment is thorough.
Coverage varies by insurance plan. As a weight management medication, some plans cover it and others don't. We recommend contacting your insurance provider. Iuventus offers transparent, reasonable pricing — consult us for specific program costs.
Start Today

Start the life
you've always wanted.

A mandatory medical consultation before starting — we confirm candidacy, review contraindications, and design the program around your specific situation. Iuventus Medical Center Las Vegas.